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rnason et al., 2018

Unlike traditional treatments that target only CSF production, GLP-1 agonists may work through two pathways: Weight loss - a major long-term treatment for IIH Possible CSF pressure effects - GLP-1 receptors on the choroid plexus (where CSF is made) may reduce fluid secretion independent of weight loss The IIH Pressure Trial ( Brain , 2023) found that exenatide lowered intracranial pressure within hours of the first dose

9 President Trump has rightly described this as global freeloading where inflated prices in the United States fuel global innovation while foreign health systems get a free ride. 10 These harsh realities and trends have been the underlying motivation behind the Trump administrations groundbreaking most favored nation policy on prescription drugsa policy that has already reaped substantial benefits

Holding weight off at this stage relies on remaining on meds and good habits